Advanced Sodium PAS Granules by Swapnroop Drugs & Pharmaceuticals

 


🌟 Sodium PAS Granules – A Modern Approach to Anti-Tuberculosis Therapy by Swapnroop Drugs & Pharmaceuticals

In the global battle against tuberculosis (TB), advanced formulations play a critical role in improving treatment outcomes and patient adherence. Sodium Para-Aminosalicylic Acid (Sodium PAS) Granules have emerged as a vital second-line anti-tuberculosis drug, known for their improved tolerability and enhanced patient compliance.

Swapnroop Drugs & Pharmaceuticals, a trusted name in high-quality pharmaceutical manufacturing, delivers superior Sodium PAS Granules designed to support effective TB treatment worldwide. 🌍💊

🔬 What Are Sodium PAS Granules?

Sodium PAS Granules are granulated forms of sodium para-aminosalicylic acid, a key second-line anti-TB medication used primarily to combat multidrug-resistant tuberculosis (MDR-TB).
These granules are specially engineered to:
✔ Reduce stomach irritation
✔ Improve taste and acceptability
✔ Enhance stability
✔ Ensure controlled drug release

Thanks to advanced formulation techniques used by Swapnroop Drugs & Pharmaceuticals, these granules offer superior performance and patient convenience. ✨

🩺 Why Sodium PAS is Important in TB Treatment?

Sodium PAS plays a crucial role in TB therapy because:

  • It inhibits folate synthesis in Mycobacterium tuberculosis 🦠

  • It is effective against MDR-TB strains

  • It works synergistically with other anti-TB drugs

  • It helps prevent resistance to key medications like isoniazid & streptomycin

In granule form, it becomes more tolerable, especially for patients requiring long-term therapy. ⏳💪

⚙️ How Swapnroop Drugs & Pharmaceuticals Manufactures Sodium PAS Granules

At Swapnroop Drugs & Pharmaceuticals, Sodium PAS Granules are produced using strict GMP-compliant processes, ensuring maximum stability and patient safety. The process includes:

🔹 Precision Blending: Pure Sodium PAS is carefully mixed with stabilizers
🔹 Controlled Granulation: Ensures uniform particle size & flowability
🔹 Enteric or Protective Coating: Reduces gastric irritation and enhances tolerability
🔹 Drying & Sieving: Maintains quality and uniformity
🔹 High-Barrier Packaging: Protects against moisture & oxidation

Each batch undergoes rigorous testing to meet global pharmaceutical standards. 🧪✔️

👨‍⚕️ Key Benefits of Sodium PAS Granules from Swapnroop Drugs & Pharmaceuticals

🌈 Enhanced Patient Compliance
Easy-to-consume granules reduce side effects and improve therapy outcomes.

💡 Better Stability & Shelf Life
Special coatings protect the drug from degradation.

🛡️ Reduced Gastrointestinal Irritation
Buffered formulations ensure smooth digestion.

🧃 Flexible Administration
Can be mixed with water, milk, or soft foods—ideal for all age groups.

🌍 Suitable for Global MDR-TB Programs
Meets international quality benchmarks.

💊 Applications of Sodium PAS Granules

Sodium PAS Granules are used in:

  • MDR-TB treatment regimens

  • Second-line anti-tuberculosis therapy

  • Combination therapy with other TB drugs

  • Cases where first-line drugs fail or cannot be tolerated

These granules ensure consistent dosing even during long treatments. 📅📈

🧪 Quality Control at Swapnroop Drugs & Pharmaceuticals

Every batch of Sodium PAS Granules undergoes strict QC tests, including:
✔ Assay & purity by HPLC
✔ Dissolution & release profile
✔ Particle size distribution
✔ Moisture content
✔ Stability testing
✔ Microbial contamination tests

Quality and safety remain top priorities. 🧬🛡️

📦 Packaging and Storage

To maintain effectiveness, Swapnroop Drugs & Pharmaceuticals uses:
📦 High-barrier laminated sachets
📦 Moisture-resistant containers
📦 Multi-layer bulk drums for export

Recommended Storage:

  • Store below 25–30°C

  • Keep away from moisture & direct sunlight

  • Use immediately after opening

🌐 Conclusion

Sodium PAS Granules by Swapnroop Drugs & Pharmaceuticals offer a reliable, patient-friendly, and clinically effective solution for treating multidrug-resistant tuberculosis. With superior manufacturing standards and globally trusted quality, these granules play a significant role in strengthening TB control efforts worldwide. 🌍💙



1️⃣ What are Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

Sodium PAS Granules by Swapnroop Drugs & Pharmaceuticals are specially formulated granules containing Sodium Para-Aminosalicylic Acid, a second-line anti-tuberculosis drug used primarily in the treatment of multidrug-resistant tuberculosis (MDR-TB). 🌍💊
These granules are designed to improve stability, reduce gastric irritation, and enhance patient compliance through advanced coating technologies.

2️⃣ What are Sodium PAS Granules used for?

Sodium PAS Granules from Swapnroop Drugs & Pharmaceuticals are used to:
✔ Treat multidrug-resistant tuberculosis (MDR-TB)
✔ Serve as a second-line therapy when first-line drugs fail
✔ Prevent resistance to other crucial anti-TB drugs
✔ Improve treatment adherence in long-term TB therapy
🦠💪

3️⃣ What are the physicochemical properties of Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

Key properties include:
⚗️ Appearance: Off-white to light tan granules
⚗️ Solubility: Freely soluble in water, stable under controlled pH
⚗️ Particle size: Uniform for smooth administration
⚗️ Taste: Enhanced acceptability due to coating
⚗️ Stability: Protected from moisture, heat & oxidation
⚗️ Purity: Meets pharmacopeial standards

These properties ensure high-quality therapeutic performance. 🌟

4️⃣ How are Sodium PAS Granules synthesized/manufactured by Swapnroop Drugs & Pharmaceuticals?

The manufacturing process includes:

🔹 Raw Material Preparation: High-purity Sodium PAS selected
🔹 Blending: Mixed with stabilizers and excipients
🔹 Granulation: Wet granulation or fluid-bed granulation
🔹 Coating (Optional): Enteric/protective coating reduces gastric irritation
🔹 Drying & Milling: Ensures uniform granule structure
🔹 Sieving: Achieves controlled particle size
🔹 Packing: High-barrier packaging to prevent degradation

All steps follow GMP-certified processes. 🏭🛡️

5️⃣ What are the different dosage forms of Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

Common dosage applications include:
💊 Granule sachets
🧃 Oral suspension (after reconstitution)
📦 Bulk granules for hospital programs
🌍 MDR-TB treatment packs

6️⃣ How are dosage forms containing Sodium PAS Granules prepared?

Preparation varies by dosage form:

🔹 For Sachets:
Pre-weighed granules are filled in laminated sachets.

🔹 For Suspension:
Granules are mixed with sweeteners, stabilizers & flavoring agents and packed as dry syrup.

🔹 For Hospital Bulk Packs:
Granules are measured into airtight drums for institutional therapy programs.

7️⃣ What is the appropriate dosage form of Sodium PAS Granules produced by Swapnroop Drugs & Pharmaceuticals?

The most effective dosage forms include:
✔ Sachets for easy administration
✔ Ready-to-mix dry powder bottles
✔ Granules for direct consumption with water or milk

These forms improve patient convenience and accuracy. 🎯

8️⃣ When should Sodium PAS Granules or their dosage forms be taken?

Sodium PAS Granules should be taken:
🕒 2 to 3 times daily, depending on therapy requirement
🍽️ Preferably after meals to reduce gastric irritation
💧 With sufficient fluids

Always follow the physician’s MDR-TB treatment guidelines. ⚕️

9️⃣ What are the effects and side effects of Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

Effects:

✔ Strong anti-tubercular action
✔ Reduces bacterial load in MDR-TB
✔ Helps prevent drug resistance

Possible Side Effects:

⚠️ Nausea
⚠️ Abdominal discomfort
⚠️ Allergic reactions (rare)
⚠️ Mild diarrhea

Advanced formulation by Swapnroop Drugs & Pharmaceuticals reduces many gastrointestinal side effects. 🌿

🔟 How are Sodium PAS Granules tested in quality control by Swapnroop Drugs & Pharmaceuticals?

QC tests include:
🔬 Assay by HPLC
🔬 Dissolution profile
🔬 pH and solubility
🔬 Moisture content
🔬 Stability testing
🔬 Microbial load
🔬 Particle size analysis

Strict QC ensures safe, stable & effective granules. 🧪✔️

1️⃣1️⃣ What tests are performed on Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

The granules undergo multiple evaluations such as:
✔ Identification tests
✔ Assay & purity tests
✔ Related substances
✔ Bulk density & flowability
✔ Loss on drying
✔ Packaging integrity tests
✔ Accelerated stability studies

1️⃣2️⃣ What are the challenges in manufacturing Sodium PAS Granules at scale for Swapnroop Drugs & Pharmaceuticals?

Major challenges include:
⚠️ Maintaining chemical stability of Sodium PAS
⚠️ Preventing degradation from heat or moisture
⚠️ Ensuring uniform granule size
⚠️ Avoiding oxidation during production
⚠️ Managing enteric coating consistency

The company overcomes these using precision-controlled machinery and airtight production environments. 🏭💡

1️⃣3️⃣ What are the challenges in manufacturing dosage forms containing Sodium PAS Granules?

Challenges include:
⚠️ Ensuring granules don’t break during blending
⚠️ Maintaining taste acceptability
⚠️ Avoiding segregation in mixtures
⚠️ Ensuring reconstitution stability in dry syrups
⚠️ Achieving uniform dosing in sachets

1️⃣4️⃣ What are the recommended storage conditions for Sodium PAS Granules by Swapnroop Drugs & Pharmaceuticals?

📌 Store below 25–30°C
📌 Keep away from moisture & direct sunlight
📌 Use airtight, laminated packaging
📌 Avoid exposure to humidity once opened

These conditions preserve potency and stability. 📦🌤️

1️⃣5️⃣ What packaging is appropriate for Sodium PAS Granules manufactured by Swapnroop Drugs & Pharmaceuticals?

The ideal packaging includes:
📦 Aluminium-laminated sachets
🛢️ HDPE airtight drums
🧴 Moisture-resistant bottles
🛡️ High-barrier multilayer pouches

Packaging is chosen to prevent oxidation and moisture degradation.


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