Ibuprofen DC Granules – Premium Direct Compression Granules by Swapnroop Drugs & Pharmaceuticals
🌟 Ibuprofen DC Granules – Premium Direct Compression Granules by
Swapnroop Drugs & Pharmaceuticals 🌟
Swapnroop
Drugs & Pharmaceuticals proudly presents Ibuprofen DC Granules, a high-quality direct
compression grade granule formulated for efficient tablet manufacturing.
Ibuprofen
is a widely used NSAID (Non-Steroidal Anti-Inflammatory Drug) that
provides:
- 🔹 Pain relief
- 🔹 Anti-inflammatory action
- 🔹 Antipyretic (fever-reducing) effects
Swapnroop’s
DC granules offer superior flow, excellent compressibility, and uniform
content, enabling manufacturers to produce consistent, robust, and
high-quality immediate-release tablets.
🧬 What Are Ibuprofen DC Granules?
Ibuprofen
DC Granules are:
- Pre-processed, ready-to-compress
granules
- Containing high-purity Ibuprofen
API
- Blended with optimized
excipients (diluents, binders, lubricants, and glidants)
- Engineered for uniform
flow, compressibility, and consistent dosing
➡️ These granules eliminate the need for wet granulation, reduce
manufacturing steps, and ensure high-yield, reproducible tablets.
🔬 Key Features & Benefits of
Ibuprofen DC Granules
For Manufacturers
- ⚡ Faster tablet production – direct
compression ready
- 🏭 Excellent flowability – uniform die
fill for high-speed rotary presses
- 💰 Cost-effective – reduced labor and
process complexity
- 📦 High content uniformity – minimal
batch-to-batch variation
For Formulators
- 💊 Optimized particle size for consistent
compressibility
- 🌡️ Enhanced stability to reduce
moisture-related issues
- 💧 Improved dissolution for rapid onset of
action
For Patients
- 💊 Accurate dosing ensures safety and efficacy
- 🌡️ Rapid relief from pain, inflammation, and
fever
⚙️ Physicochemical Properties of
Ibuprofen DC Granules
|
Property |
Description |
|
Appearance |
Off-white
to white free-flowing granules ⚪ |
|
Particle
Size |
Optimized
for uniform die fill 📏 |
|
Flowability |
Excellent
for high-speed presses ⏩ |
|
Bulk
& Tapped Density |
Optimized
for compressibility ⚖️ |
|
Moisture
Content |
≤2% 🌬️ |
|
Solubility |
Poor in
water; soluble in organic solvents 💧 |
|
Assay |
Meets
IP/BP/USP standards 🧪 |
|
Stability |
Resistant
to heat and moisture when stored properly ✅ |
These
properties ensure smooth compression, robust tablets, and predictable
dissolution.
🏭 Manufacturing Process
Swapnroop
follows a strict GMP-compliant process for producing Ibuprofen DC
Granules:
- API Micronization – reduces particle size for
better dissolution 🌬️
- Pre-Blending with Excipients – ensures uniform
distribution 🔄
- Granulation – dry or fluid-bed
granulation for uniform granule formation ⚙️
- Drying & Sieving – moisture controlled to
<2%, uniform particle size 📏
- Lubrication & Final
Blending –
smooth compression and easy ejection 🏭
- QC Testing & Packaging – assay, moisture, flow, stability,
microbial limits 🧪
This
ensures high-quality granules ready for direct compression, reducing
time and production costs.
💊 Applications & Dosage Forms
Ibuprofen
DC Granules are
primarily used to manufacture:
- 💊 Immediate-release tablets
- 💊 Film-coated tablets (for taste masking or
aesthetic purposes)
- 💊 Chewable or dispersible tablets
- 💊 Combination tablets with other analgesics or
antipyretics
These
forms provide rapid onset of action, which is essential for pain and
fever management.
🧪 Advantages of Swapnroop Ibuprofen DC
Granules
- ⚡ Direct Compression Ready – reduces
processing steps and time
- 🏋️ High Tablet Strength & Low Friability
– ensures mechanical robustness
- 💧 Enhanced Dissolution – faster
therapeutic effect
- 🧿 Uniform Dose Delivery
– critical for safety and efficacy
- 🌡️ Stable under standard storage conditions
– reduces degradation and moisture issues
📦 Packaging, Storage &
Shelf-Life
- Packaging: HDPE drums or triple-layer
moisture-proof polybags
- Storage Conditions: Store in a cool, dry place
away from sunlight
- Shelf-Life: 24–36 months based on
stability studies
Swapnroop
provides Certificate of Analysis (COA) and regulatory support for
international markets.
🧪 Quality Control & Testing Parameters
Comprehensive
QC includes:
Physical Tests:
- Flowability ⏩
- Bulk & tapped density ⚖️
- Particle size distribution 📏
- Moisture content 🌬️
Chemical Tests:
- API assay (%) 🧪
- Content uniformity ✅
- Related substances /
impurities 🔬
Performance Tests:
- Tablet hardness &
friability 🏋️
- Disintegration &
dissolution 💧
- Stability under accelerated
& long-term conditions ⏳
Microbiological Tests:
- Total viable count
- Absence of harmful
microorganisms
All tests
meet IP/BP/USP standards, ensuring global compliance.
🌟 Conclusion
Ibuprofen
DC Granules by Swapnroop Drugs & Pharmaceuticals provide:
- 💊 High-quality, uniform, ready-to-compress
granules
- ⚙️ Efficient, cost-effective tablet
manufacturing
- 💧 Fast onset of action for pain, inflammation,
and fever relief
- 🌍 Compliance with international pharmacopeial
standards
💊✨ Ibuprofen DC Granules – Reliable quality,
efficient production, rapid relief.
Q1️⃣. What are Ibuprofen DC Granules manufactured by
Swapnroop Drugs & Pharmaceuticals?
Answer:
Ibuprofen DC Granules are pre-processed, ready-to-compress granules
containing high-purity Ibuprofen API blended with optimized excipients
such as:
- Microcrystalline cellulose
(diluents) 🏭
- Polyvinylpyrrolidone
(binders) 🧬
- Magnesium stearate
(lubricants) ⚙️
- Colloidal silicon dioxide
(glidants) 🌬️
These
granules are engineered for direct compression tablet manufacturing,
providing:
- 💊 Uniform dose per tablet
- ⚡ Excellent flow for high-speed rotary
presses
- 🏭 Reproducible compression and tablet
hardness
- 📦 Efficient production with minimal
processing steps
Swapnroop
ensures GMP-compliant, regulatory-ready production, suitable for
domestic and global markets.
Q2️⃣. What is the primary use of Ibuprofen DC Granules?
Answer:
Ibuprofen DC Granules are designed for the production of oral tablets for
pain, inflammation, and fever relief:
- 🌡️ Reduces fever and alleviates pyrexia
- 🦵 Relieves
musculoskeletal pain, headaches, and arthritic pain
- 🫁 Provides
anti-inflammatory action in conditions like rheumatoid arthritis
- 💊 Suitable for monotherapy or combination
tablets (with paracetamol or caffeine)
DC
granules ensure accurate dosing and consistent therapeutic efficacy in
every tablet.
Q3️⃣. What are the physicochemical properties of
Ibuprofen DC Granules?
Answer:
|
Property |
Description |
|
Appearance |
Off-white
to white free-flowing granules ⚪ |
|
Particle
Size |
Optimized
for uniform die fill and compressibility 📏 |
|
Flowability |
Excellent
⏩ |
|
Bulk
Density |
0.45–0.55
g/mL ⚖️ |
|
Tapped
Density |
0.55–0.65
g/mL ⚖️ |
|
Moisture
Content |
≤2% 🌬️ |
|
Solubility |
Poor in
water, soluble in organic solvents 💧 |
|
Assay |
Meets
IP/BP/USP standards 🧪 |
|
Melting
Point (API) |
75–78°C
🌡️ |
|
Stability |
Resistant
to heat and moisture ✅ |
These
properties ensure consistent compression, uniform content, and reliable
dissolution in the final tablet.
Q4️⃣. How are Ibuprofen DC Granules manufactured?
Answer:
The manufacturing process is strictly GMP-compliant and includes:
- API Micronization – reduces particle size for
enhanced dissolution 🌬️
- Pre-Blending – uniform distribution of
API with excipients 🔄
- Granulation – dry, fluid-bed, or roller
compaction ⚙️
- Drying & Sieving – controlled moisture
(<2%) and uniform particle size 📏
- Lubrication & Final
Blending –
ensures smooth compression 🏭
- QC Testing – physical, chemical,
microbiological, and stability tests 🧪
- Packaging – moisture-resistant, HDPE
drums or triple-layer polybags 📦
This
method ensures high-quality granules ready for direct compression,
reducing manufacturing time and cost.
Q5️⃣. What dosage forms can be manufactured using
Ibuprofen DC Granules?
Answer:
Ibuprofen DC Granules are versatile for:
- 💊 Immediate-release tablets
- 💊 Film-coated tablets (for taste masking or
gastro-resistance)
- 💊 Chewable or dispersible tablets
- 💊 Combination tablets with other analgesics,
antipyretics, or NSAIDs
The
granules enable high-speed tableting, robust mechanical properties, and
uniform API distribution.
Q6️⃣. How are these dosage forms prepared?
Answer:
Preparation uses direct compression, which involves:
- Blending DC granules with
lubricants and glidants ⚙️
- Compressing into tablets
using rotary or single-punch presses 🏭
- Optional film coating for taste masking or
stability 🎨
Advantages
of DC process:
- Eliminates wet granulation 🌊
- Reduces production steps ⏱️
- Minimizes batch loss and
contamination 🧹
This
ensures uniform, stable, and high-quality tablets.
Q7️⃣. Which dosage form is most appropriate?
Answer:
Immediate-release (IR) tablets are preferred:
- ⚡ Provide rapid relief from pain, inflammation,
and fever
- 💊 Offer predictable pharmacokinetics and fast
onset of action
- ✅ Compatible with combination therapies (e.g.,
with paracetamol)
DC granules ensure optimal dissolution, content uniformity, and mechanical strength.
Q8️⃣. When should Ibuprofen tablets be taken?
Answer:
- ⏰ Typically every 6–8
hours as prescribed by a physician
- 💧 Should be taken with water or food to reduce
gastrointestinal irritation
- 🧿 Consistent timing
ensures steady plasma concentration and efficacy
- ⚠️ Avoid exceeding maximum daily dose (usually
1200–2400 mg for adults depending on formulation)
DC
granules guarantee accurate dosing in every tablet, enhancing patient
safety.
Q9️⃣. What are the therapeutic effects and side effects
of Ibuprofen?
Answer:
Therapeutic Effects:
- 💊 Analgesic – relieves mild to moderate pain
- 🫀 Anti-inflammatory
– reduces inflammation in musculoskeletal disorders
- 🌡️ Antipyretic – lowers fever
- 🧿 Supports symptom
relief in osteoarthritis, rheumatoid arthritis, and headaches
Side Effects:
- 🤢 Nausea, vomiting,
or gastrointestinal upset
- 🩸 Rare
gastrointestinal bleeding with prolonged use
- 🌀 Dizziness or headache
- ⚠️ Allergic reactions in sensitive individuals
- 💔 Long-term use may impact renal or
cardiovascular function
Q🔟. What tests are performed on
Ibuprofen DC Granules at Swapnroop Drugs & Pharmaceuticals?
Answer:
Comprehensive Quality Control ensures global compliance:
Physical Tests:
- Flowability ⏩
- Bulk & tapped density ⚖️
- Particle size distribution 📏
- Moisture content 🌬️
Chemical Tests:
- API assay (%) 🧪
- Content uniformity ✅
- Related substances /
impurities 🔬
Performance Tests:
- Tablet hardness &
friability 🏋️
- Disintegration &
dissolution 💧
- Accelerated & long-term
stability ⏳
Microbiological Tests:
- Total viable count
- Absence of harmful
microorganisms
All
parameters meet IP/BP/USP standards, ensuring safe, effective, and
regulatory-compliant tablets.
✅ Conclusion:
Ibuprofen DC Granules by Swapnroop Drugs & Pharmaceuticals provide:
- 💊 High-quality, ready-to-compress granules
- ⚙️ Efficient and cost-effective manufacturing
- 💧 Rapid onset of analgesic, anti-inflammatory,
and antipyretic effects
- 🌍 Compliance with international pharmacopeial
standards
💊✨ Ibuprofen DC Granules – Consistent quality,
efficient production, rapid relief.
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