Atorvastatin Calcium Trihydrate API (CAS No: 134523-03-8): Complete Guide to Uses, Benefits & Pharmaceutical Insights

Introduction

Atorvastatin Calcium Trihydrate API (CAS No: 134523-03-8) is a widely recognized pharmaceutical active ingredient used in the treatment of lipid disorders and cardiovascular conditions. It plays a vital role in cholesterol management therapies and is a key component in modern cardiovascular drug formulations.

Atorvastatin-Calcium-Trihydrate-API-CAS-No-134523-03-8-Complete-Guide-to-Uses-Benefits-Pharmaceutical-Insights

With the increasing prevalence of heart-related diseases, the demand for high-quality statin APIs and cardiovascular pharmaceutical ingredients continues to grow globally.

What is Atorvastatin Calcium Trihydrate?

Atorvastatin Calcium Trihydrate is a well-established lipid-lowering agent belonging to the statin drug class. It is primarily used in the development of cholesterol-reducing medications.

Key Details:

• CAS Number: 134523-03-8
• Category: Antihyperlipidemic API
• Form: Trihydrate (enhanced stability form)
• Applications: Oral solid dosage formulations such as tablets and capsules

Mechanism of Action

Atorvastatin works by inhibiting the enzyme HMG-CoA reductase inhibitor pathway, which is responsible for cholesterol synthesis in the liver.

This leads to:

• Reduction in LDL cholesterol levels
• Increase in HDL cholesterol levels
• Decrease in triglyceride levels

These benefits contribute to effective cardiovascular risk reduction and improved patient outcomes.

Key Uses of Atorvastatin Calcium Trihydrate API

1. Treatment of Hypercholesterolemia

Used in cholesterol-lowering treatments to manage high lipid levels.

2. Prevention of Cardiovascular Diseases

Supports heart disease prevention therapies and reduces risks of stroke.

3. Dyslipidemia Management

Helps regulate abnormal lipid profiles in patients.

4. Long-Term Cardiac Care

Widely used in chronic cardiovascular therapy for sustained health benefits.

Benefits of Atorvastatin API

• Proven effectiveness in reducing bad cholesterol (LDL)
• Long-lasting effect in lipid control therapy
• Suitable for long-term pharmaceutical use
• Widely accepted in global generic drug manufacturing
• Strong track record in clinical safety and efficacy

Manufacturing & Quality Standards

The production of Atorvastatin Calcium Trihydrate API follows strict pharmaceutical manufacturing standards to ensure:

• High purity active pharmaceutical ingredient quality
• Consistent batch uniformity
• Compliance with global regulatory guidelines
• Availability of regulatory documentation (COA, DMF)

Global Market Insights

The demand for Atorvastatin continues to grow due to:

• Rising cases of cardiovascular disorders worldwide
• Increasing adoption of preventive healthcare solutions
• Expansion of generic pharmaceutical production

This API remains a critical component in global pharmaceutical supply chains.

Storage & Handling

• Store under controlled temperature conditions
• Protect from moisture and light exposure
• Maintain in airtight pharmaceutical containers
• Follow standard API storage guidelines

About Us – Swapnroop Drugs and Pharmaceuticals

At Swapnroop Drugs and Pharmaceuticals, we take pride in being a trusted global supplier of pharmaceutical raw materials, delivering excellence, reliability, and regulatory compliance since 2013.

We specialize in:

• High-quality Active Pharmaceutical Ingredients (APIs)
• Reliable global distribution support
• Strict adherence to GMP-compliant sourcing practices
• Long-term pharmaceutical industry partnerships

Conclusion

Atorvastatin Calcium Trihydrate API (CAS No: 134523-03-8) remains a cornerstone in cholesterol management and cardiovascular treatment. Its proven performance, safety, and widespread use make it an essential component in modern pharmaceutical formulations.

With the growing demand for cardiovascular therapies and lipid-lowering medications, choosing a reliable and quality-focused partner ensures long-term success, regulatory compliance, and consistent product performance in the pharmaceutical industry.

Frequently Asked Questions (FAQs)

1. What is Atorvastatin Calcium Trihydrate API used for?

It is used in the production of cholesterol-lowering medications and cardiovascular treatment drugs.

2. What is the advantage of the trihydrate form?

The trihydrate form improves stability in pharmaceutical formulations and enhances product performance.

3. Is this API suitable for long-term therapy?

Yes, it is widely used in chronic lipid management treatments and long-term care.

4. In which dosage forms is it commonly used?

It is primarily used in oral solid dosage forms such as tablets and capsules.

5. What are the ideal storage conditions?

It should be stored under controlled pharmaceutical storage conditions, away from moisture and sunlight.

6. Why choose Swapnroop Drugs and Pharmaceuticals as your API partner?

Swapnroop Drugs and Pharmaceuticals provide high-quality pharmaceutical APIs, consistent supply, regulatory compliance, and reliable global service — making us a dependable partner since 2013.