Clindamycin Hydrochloride API (CAS No: 21462-39-5): Complete Guide for Buyers, Manufacturers & Suppliers
Clindamycin Hydrochloride API is an important pharmaceutical active ingredient widely used in the formulation of antibacterial medicines. It belongs to the lincosamide class of antibiotics and is known for its effectiveness against several bacterial infections. In today’s pharmaceutical market, demand for dependable antibiotic APIs remains strong, making high-quality sourcing essential for manufacturers, traders, and contract formulators.
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| Clindamycin-Hydrochloride API-CAS-No-21462-39-5-Complete-Guide-for-Buyers-Manufacturers-&-Suppliers |
As healthcare systems expand and antibiotic manufacturing continues across domestic and export markets, pharmaceutical companies look for suppliers who can provide consistent quality, regulatory documentation, and timely deliveries. That is where a trusted Clindamycin Hydrochloride manufacturer supplier in India becomes highly valuable.
India has emerged as one of the leading global hubs for API production due to strong manufacturing infrastructure, technical expertise, and cost competitiveness. Buyers increasingly prefer Indian API companies that can meet GMP standards while maintaining stable supply chains. For businesses involved in capsule, tablet, suspension, or specialty dosage manufacturing, selecting the right supplier directly impacts production timelines and finished product quality.
This guide explains everything you need to know about Clindamycin Hydrochloride API (CAS No: 21462-39-5) including chemical profile, applications, market demand, compliance expectations, and why reliable sourcing matters.
What is Clindamycin Hydrochloride API
Clindamycin Hydrochloride is the hydrochloride salt form of clindamycin, a semi-synthetic antibiotic derived from lincomycin. It is widely used as an oral pharmaceutical ingredient and appears commonly in capsules and other dosage forms. It works by inhibiting bacterial protein synthesis through action on the 50S ribosomal subunit.
Classification and Drug Category
It is classified as:
- Therapeutic Class: Antibiotic
- Chemical Class: Lincosamide antibiotic
- Dosage Role: Active Pharmaceutical Ingredient (API)
- Common Use: Human pharmaceutical formulations
How It Works
The API helps stop bacterial growth by interfering with protein production required for bacterial survival. In simple terms, it cuts the communication line inside harmful bacteria, limiting their ability to multiply. That mechanism makes it a widely recognized antibacterial ingredient for prescription drug manufacturing.
For pharmaceutical companies, the importance lies not only in clinical value but also in formulation compatibility, availability, and stable production supply.
Key Chemical / Technical Information
Accurate technical specifications are essential when evaluating any API supplier. Clindamycin Hydrochloride CAS No: 21462-39-5 is globally recognized under this registry number.
| Parameter | Details |
|---|---|
| Product Name | Clindamycin Hydrochloride |
| CAS Number | 21462-39-5 |
| Molecular Formula | C18H34Cl2N2O5S |
| Molecular Weight | 461.44 g/mol |
| API Category | Antibiotic |
| Storage Condition | Cool, dry place / controlled storage |
| Solubility | Soluble in water |
Solubility and Storage
The compound demonstrates water solubility and is generally handled under controlled storage conditions. Some references list storage guidance at 2–8°C depending on grade and intended use.
When purchasing bulk material, buyers should always confirm:
- Latest COA
- Retest period
- Impurity profile
- Moisture limits
- Packing configuration
- Regulatory support documents
Properties and Composition
The physical profile of Clindamycin Hydrochloride API plays an important role during formulation and production. It is generally supplied as a white to off-white powder, depending on grade and manufacturing process. Controlled particle size, purity, and moisture limits are often required for smooth blending and encapsulation processes.
Important properties often evaluated by procurement and QA teams include:
- Assay purity
- Residual solvents
- Heavy metals compliance
- Microbial limits (where applicable)
- Bulk density
- Flow characteristics
Think of API quality like the foundation of a building. If the base material is inconsistent, everything built on top of it becomes risky. The same principle applies in pharmaceuticals. Even minor quality variations can affect dissolution, blend uniformity, or finished dosage performance.
Reliable manufacturers maintain strict batch-to-batch consistency supported by validated analytical methods such as HPLC and pharmacopeial standards. That consistency helps formulation plants reduce rejections, save production time, and maintain product reliability.
Benefits and Functional Advantages
Why do pharmaceutical companies continue to source Clindamycin Hydrochloride bulk API? Because it offers multiple commercial and formulation advantages.
First, it is a recognized antibiotic ingredient with established demand in pharmaceutical markets. Products containing this API are widely manufactured, which supports continuous industrial consumption.
Second, it can be formulated into convenient oral dosage forms. Manufacturers value APIs that integrate smoothly into scalable production systems.
Third, Indian sourcing often offers a strong balance between quality and commercial viability. Buyers can obtain cost-effective supply without compromising documentation or standards when partnering with the right company.
Key advantages include:
- Strong pharmaceutical market relevance
- Reliable demand across regions
- Suitable for multiple oral dosage formats
- Scalable bulk manufacturing potential
- Export opportunity support
- Competitive sourcing economics
For procurement teams, this means a practical combination of therapeutic relevance and business viability.
Applications / Uses in Industry
Pharmaceutical Formulations
Clindamycin Hydrochloride API is mainly used in manufacturing:
- Capsules
- Tablets (depending on formulation strategy)
- Oral suspensions
- Combination products
- Hospital supply formulations
Contract Manufacturing
Third-party pharma manufacturers and loan license units often require dependable API vendors who can maintain regular dispatch schedules. A delayed API shipment can halt an entire production line. That is why companies prioritize suppliers with ready stock and logistics capability.
In regulated and semi-regulated markets, buyers may also request:
- DMF support (if available)
- Stability data
- Validation support
- Method transfer documentation
The broader pharmaceutical ecosystem depends heavily on API reliability, and Clindamycin Hydrochloride remains part of that supply chain.
Manufacturing Process Overview
While proprietary manufacturing routes vary by producer, Clindamycin Hydrochloride is generally produced through controlled semi-synthetic processing followed by purification, salt formation, drying, milling, and quality testing.
A professional manufacturing cycle usually includes:
- Raw material qualification
- Reaction control under validated conditions
- Purification stages
- Salt conversion to hydrochloride form
- Drying and particle size control
- Analytical release testing
- GMP packaging and dispatch
The best API manufacturers operate like precision clockmakers. Every stage must align perfectly—temperature, pH, filtration, drying, and testing. One small deviation can impact quality.
That is why pharmaceutical buyers should choose manufacturers with strong SOP systems, trained technical staff, validated equipment, and documented quality assurance practices.
Market Demand and Trends (India + Global)
The global antibiotic market continues to support steady demand for essential antibacterial APIs. While pricing cycles may fluctuate due to raw material availability, regulatory changes, freight costs, and demand shifts, anti-infective APIs remain strategically important.
India is one of the world’s major API manufacturing centers and continues to expand exports. Domestic demand is also strong because India has a vast formulations industry serving both prescription and institutional markets.
Current procurement trends include:
- Preference for GMP-compliant Indian suppliers
- Multi-source risk management
- Need for ready stock availability
- Faster documentation turnaround
- Competitive bulk pricing
- Stable long-term supply contracts
For buyers, the market message is clear: quality alone is not enough anymore. Speed, consistency, communication, and logistics matter just as much.
Quality Standards and Compliance
For pharmaceutical APIs, compliance is non-negotiable. Buyers should verify that their Clindamycin Hydrochloride supplier in Maharashtra India or elsewhere can support recognized quality systems.
Common expectations include:
- GMP-compliant manufacturing
- COA with every batch
- Traceability systems
- Controlled warehousing
- Change control practices
- Batch consistency records
- Documentation support
Depending on customer geography, additional requirements may include pharmacopeial alignment such as IP, BP, USP, or EP specifications.
A professional supplier should be transparent, responsive, and audit-ready. If a supplier struggles to answer technical questions quickly, that often signals future supply challenges.
Packaging, Storage and Stability
Correct packaging protects API integrity during storage and transportation. Bulk pharmaceutical ingredients are commonly packed in moisture-protective inner liners with secure external drums or fiber containers.
Best practices include:
- Keep tightly closed
- Protect from heat and moisture
- Store in recommended conditions
- Use FIFO inventory rotation
- Avoid cross-contamination exposure
Long-distance shipping requires equal attention. A quality product packed poorly can arrive compromised. That is why packaging standards matter as much as assay results.
Why Choosing the Right Manufacturer Supplier Matters
Choosing the wrong supplier may save money on paper but cost heavily in delays, batch failures, rejected documentation, or missed export deadlines.
The right Bulk Clindamycin Hydrochloride Manufacturer Supplier in India offers:
- Consistent batch quality
- Reliable stock position
- Competitive pricing
- Fast dispatch
- Technical support
- Transparent communication
- Long-term business trust
In pharmaceutical procurement, trust is not built by promises. It is built by every batch delivered correctly and on time.
About Swapnroop Drugs and Pharmaceuticals
Swapnroop Drugs and Pharmaceuticals is a leading pharmaceutical raw materials manufacturer and exporter based in Maharashtra, India, offering a comprehensive portfolio of APIs, excipients, pellets, and granules. The company supports pharmaceutical and biotech industries with high-quality, GMP-compliant products designed to meet international standards.
Its strong distribution network supports supply across major pharmaceutical hubs including Mumbai, Pune, Nagpur, Nashik, Thane, Ahmedabad, Vadodara, Ankleshwar, Surat, Hyderabad, Bangalore, Chennai, Visakhapatnam, New Delhi, Noida, Gurgaon, Chandigarh, Baddi, Haridwar, Indore, Kolkata, and Bhubaneswar.
With advanced manufacturing practices and strict quality systems, the company is recognized as a trusted API manufacturer and supplier in India and global markets, known for consistent quality, competitive pricing, and dependable logistics support.
Conclusion
Clindamycin Hydrochloride API (CAS No: 21462-39-5) remains an important antibacterial pharmaceutical ingredient with steady industrial demand. For formulation companies, traders, and exporters, success depends on sourcing from a reliable and compliant partner.
When evaluating suppliers, focus on product quality, documentation readiness, packaging standards, dispatch reliability, and long-term consistency. A strong supply partner does more than sell material—they help your production line keep moving.
If you are seeking a dependable Pharmaceutical Clindamycin Hydrochloride Manufacturer Supplier, India offers strong advantages in quality manufacturing and commercial competitiveness.
FAQs
1. What is Clindamycin Hydrochloride API used for?
It is used as an active pharmaceutical ingredient in antibiotic formulations such as capsules and oral dosage products.
2. What is the CAS number of Clindamycin Hydrochloride?
The CAS number is 21462-39-5.
3. Is Clindamycin Hydrochloride available in bulk supply?
Yes, qualified API manufacturers and exporters supply it in commercial bulk quantities.
4. How should Clindamycin Hydrochloride be stored?
Store in tightly closed containers under recommended cool and dry conditions as per specification.
5. Why choose an Indian manufacturer for this API?
India offers strong pharmaceutical manufacturing infrastructure, cost efficiency, and export experience.
6. Why choose Swapnroop Drugs and Pharmaceuticals?
Swapnroop Drugs offers quality-focused manufacturing, reliable supply, competitive pricing, and broad distribution support across India and overseas markets.
Clindamycin Hydrochloride Manufacturer Supplier in India (City Coverage)
We are a trusted Clindamycin Hydrochloride manufacturer supplier in India, offering high-quality products with reliable bulk supply, consistent quality, and timely delivery across major industrial and pharmaceutical hubs.
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