Nitrofurantoin SR Pellets (CAS No: 67-20-9): Complete Guide for Pharmaceutical Applications
Introduction to Nitrofurantoin SR Pellets
When it comes to urinary tract infection (UTI) treatments, Nitrofurantoin has been a trusted name for decades. But modern pharmaceutical needs go beyond just effectiveness—they demand controlled release, better patient compliance, and optimized bioavailability. That’s exactly where Nitrofurantoin SR Pellets (CAS No: 67-20-9) step in. These sustained-release pellets are engineered to deliver the active ingredient gradually, ensuring prolonged therapeutic action and reduced dosing frequency.
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| Nitrofurantoin-SR-Pellets-CAS No 67-20-9-Complete-Guide-for-Pharmaceutical-Applications |
Imagine taking a medication that works steadily throughout the day instead of wearing off too quickly. That’s the promise of sustained-release pellets. In today’s competitive pharmaceutical landscape, such innovations are not just beneficial—they’re essential. Pharmaceutical manufacturers and formulation scientists are increasingly turning toward SR pellet technology to enhance drug performance while maintaining patient comfort.
In India and globally, the demand for high-quality Nitrofurantoin SR Pellets manufacturer suppliers is rising due to increased UTI cases and the need for reliable antibiotic formulations. This blog explores everything you need to know—from chemical properties to market trends—making it a complete resource for pharma professionals and buyers alike.
What is Nitrofurantoin SR Pellets
Nitrofurantoin SR Pellets are modified-release pharmaceutical formulations designed to deliver Nitrofurantoin in a controlled manner over an extended period. Unlike immediate-release versions, these pellets release the drug slowly, maintaining consistent plasma levels and improving therapeutic outcomes.
Understanding Sustained Release Technology
Sustained-release (SR) technology works like a time-controlled delivery system. Instead of dumping the drug all at once into the body, the pellets are coated with polymers that regulate how quickly the active ingredient dissolves. This means fewer side effects, better absorption, and improved patient adherence.
From a formulation perspective, SR pellets are often used in capsules or tablets, offering flexibility in dosage design. Pharmaceutical companies prefer these systems because they allow customization based on specific treatment needs. This innovation has made Nitrofurantoin SR pellets a preferred choice in modern drug development.
Key Chemical / Technical Information
Chemical Identity and CAS Details
Nitrofurantoin is a well-known antibacterial agent with the CAS Number 67-20-9. It belongs to the nitrofuran class of antibiotics and is primarily used to treat bacterial infections of the urinary tract.
Molecular Structure and Formula
| Property | Details |
|---|---|
| Chemical Name | Nitrofurantoin |
| CAS Number | 67-20-9 |
| Molecular Formula | C8H6N4O5 |
| Molecular Weight | 238.16 g/mol |
| Drug Class | Nitrofuran Antibiotic |
The molecular structure plays a critical role in its antibacterial activity, allowing it to interfere with bacterial enzyme systems and inhibit growth effectively.
Properties and Composition
Physical Properties
Nitrofurantoin SR pellets typically appear as yellow crystalline particles with a characteristic odor. They are slightly soluble in water but show improved dissolution when formulated into sustained-release pellets.
Composition and Excipients
The pellets are composed of:
- Active pharmaceutical ingredient (API): Nitrofurantoin
- Polymer coatings for sustained release
- Binder and filler materials
- Stabilizers for enhanced shelf life
These components work together to ensure consistent drug delivery and stability over time.
Benefits and Functional Advantages
Sustained Drug Release Benefits
One of the biggest advantages of Nitrofurantoin SR pellets is their ability to maintain steady drug levels in the bloodstream. This reduces fluctuations that can lead to side effects or reduced efficacy. Patients benefit from fewer doses per day, which significantly improves treatment adherence.
Patient Compliance and Efficiency
Think about it—would you rather take medicine multiple times a day or just once? SR pellets make life easier for patients, especially those undergoing long-term treatment. Additionally, they reduce gastrointestinal irritation, a common issue with immediate-release antibiotics.
For pharmaceutical companies, this translates into high-demand formulations that are both effective and marketable.
Applications / Uses in Industry
Pharmaceutical Applications
Nitrofurantoin SR pellets are widely used in the production of:
- Capsules
- Tablets
- Combination drug formulations
They are especially valuable in controlled-release antibiotic therapies, making them a staple in pharmaceutical manufacturing.
Therapeutic Uses
The primary use of Nitrofurantoin is in treating urinary tract infections (UTIs) caused by susceptible bacteria. Its targeted action in the urinary tract makes it highly effective with minimal systemic impact.
Manufacturing Process Overview
Pelletization Techniques
The manufacturing of SR pellets involves advanced techniques such as:
- Extrusion and spheronization
- Fluidized bed coating
- Layering processes
Each step is carefully controlled to ensure uniform size, shape, and drug release characteristics.
Quality Control in Manufacturing
Quality control is critical in pharmaceutical production. Parameters like particle size distribution, dissolution rate, and stability are rigorously tested to meet global standards.
Market Demand and Trends (India + Global)
Indian Pharmaceutical Market Insights
India is one of the largest producers of pharmaceutical products globally. The demand for bulk Nitrofurantoin SR pellets manufacturer suppliers in India is increasing due to:
- Rising UTI cases
- Expansion of generic drug manufacturing
- Growing export opportunities
Global Demand and Growth
Globally, the antibiotic market continues to grow, with sustained-release formulations gaining popularity. Nitrofurantoin remains a preferred choice due to its effectiveness and safety profile.
Quality Standards and Compliance
Nitrofurantoin SR pellets must comply with international standards such as:
- GMP (Good Manufacturing Practices)
- WHO guidelines
- USFDA and EU regulations
These standards ensure product safety, efficacy, and consistency across batches.
Packaging, Storage and Stability
Proper packaging is essential to maintain product integrity. Nitrofurantoin SR pellets are typically packed in:
- HDPE containers
- Aluminum foil bags
They should be stored in a cool, dry place away from light and moisture. Stability studies ensure a long shelf life under recommended conditions.
Why Choosing the Right Manufacturer Supplier Matters
Selecting the right supplier can make or break your pharmaceutical product. A reliable Nitrofurantoin SR pellets supplier in Maharashtra India ensures:
- Consistent quality
- Timely delivery
- Regulatory compliance
Poor-quality materials can lead to product recalls, regulatory issues, and loss of reputation. That’s why partnering with a trusted manufacturer is crucial.
Company Overview
Swapnroop Drugs and Pharmaceuticals is a leading pharmaceutical raw materials manufacturer and exporter based in Maharashtra, India, offering a comprehensive portfolio of APIs, excipients, pellets, and granules. The company supports pharmaceutical and biotech industries with high-quality, GMP-compliant products designed to meet international standards.
Our strong distribution network enables us to supply APIs across major pharmaceutical hubs—including Mumbai, Pune, Nagpur, Nashik, Thane, Ahmedabad, Vadodara, Ankleshwar, Surat, Hyderabad, Bangalore, Chennai, Visakhapatnam, New Delhi, Noida, Gurgaon, Chandigarh, Baddi, Haridwar, Indore, Kolkata, and Bhubaneswar—across India and globally.
With advanced manufacturing practices and strict quality control systems, Swapnroop Drugs ensures consistency, purity, and regulatory compliance across its product range. We are recognized as a trusted API manufacturer and supplier in India and worldwide, known for consistent quality, competitive pricing, and reliable logistics support.
We specialize in bulk API supply for pharmaceutical companies and traders across India and global markets, with ready stock availability. Our diverse portfolio serves multiple therapeutic segments, helping pharmaceutical companies accelerate drug development and production. As a reliable name in the pharmaceutical industry, Swapnroop Drugs continues to expand its global presence through innovation, quality assurance, and customer satisfaction.
Conclusion
Nitrofurantoin SR Pellets (CAS No: 67-20-9) represent a significant advancement in pharmaceutical drug delivery systems. Their ability to provide controlled release, improve patient compliance, and enhance therapeutic effectiveness makes them a valuable asset in modern medicine. With increasing demand in both Indian and global markets, the importance of sourcing high-quality pellets from trusted manufacturers cannot be overstated.
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Nitrofurantoin SR Pellets Manufacturer Supplier in India (City Coverage)
We are a trusted Nitrofurantoin SR Pellets manufacturer supplier in India, offering high-quality products with reliable bulk supply, consistent quality, and timely delivery across major industrial and pharmaceutical hubs.
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